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Junior Clinical Research Fellow in Renal Transplantation
Royal Free London NHS Foundation Trust View all jobs
Posted 25 day(s) ago
Reference: 391-RFL-8201900
Job summary
Applications are invited for a Clinical Research Fellow to support the conduct of the PROSPECT Study - Physiological Response to Once-Daily Tacrolimus (LCP-T) - at the Royal Free Hospital.
This is a fully funded research post delivered within the Renal, Nephrology and Renal Transplant Services, working under the supervision of the Principal Investigator, Dr Rhys Evans. The post-holder will support delivery of Phase 1 and Phase 2 research activity in accordance with the study protocol, NIHR and GCP standards.
The study is supported through research funding provided by Chiesi Ltd to the Royal Free London NHS Foundation Trust. This funding supports research personnel, materials and delivery of study milestones.
This post is exclusively research-focused with no clinical service commitment.
Main duties of the job
The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.
Phase 1 includes large-scale metabolomic and biochemical analysis in approximately 600 transplant recipients to characterise drug exposure profiles and identify predictors of variability.
Phase 2 involves detailed sub-study monitoring of 40 transplant patients (20 kidney, 10 liver, 10 control) to explore longitudinal changes in drug exposure, biomarkers and immunological response. The post-holder will assist with recruitment, participant follow-up, data acquisition and sample handling.
This role provides experience in transplant research, specialist assay methodologies and regulated delivery of commercial-supported studies. The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.
About us
The Royal Free London NHS Foundation Trust is one of the UK's biggest and most innovative trusts. Across three main hospitals, our dedicated army of staff care for over 1.6million patients, treat more than 200,000 in A&E, deliver over 8,000 babies and carry out more than 17million tests.
Our size, scale and influence offer you unrivalled career opportunities and a forward-thinking approach to working that works around your lifestyle. From flexible hours and generous benefits, to next level training, we make it easier to take your career to the top
For more information please follow linkhttps://www.royalfreelondonjobs.co.uk/
Details
Date posted
18 August 2026
Pay scheme
Hospital medical and dental staff
Grade
Doctor - other
Salary
£54,499 a year per annum plus London Weighting
Contract
Fixed term
Duration
24 months
Working pattern
Full-time
Reference number
391-RFL-8201900
Job locations
Royal Free Hospital
Pond Street
Hampstead
NW3 2QG
United Kingdom
Job description
Job responsibilities
Please see attached job description for more information about this role and working at Royal Free London NHS Foundation Trust.
Job description
Job responsibilities
Please see attached job description for more information about this role and working at Royal Free London NHS Foundation Trust.
Person Specification
Royal Free World Class Values
Essential
- Demonstrable ability to meet the Trust Values
Education & professional Qualifications
Essential
- MBBS or equivalent
- Full GMC registration with license to practice
- Good Clinical Practice Training Certificate
Desirable
- Membership of relevant Royal College or oversees equivalent
Experience
Essential
- Work in a clinical trials or research environment
- Experience in data collection, management, analysis and presentation
Desirable
- Relevant experience in medical specialities
- Experience in transplant or immunology field
- Involvement in the clinical audit process and an understanding of the aims thereof
Skills and aptitudes
Essential
- Excellent communication skills/verbal and written
- Ability to take on tasks and responsibilities in a multi-professional team and to be able to work effectively and sensitively within it
Desirable
- Proven ability in relevant subject areas
Personal Qualities and atributes
Essential
- Ability to organise and prioritise workload
- High ethical and professional standards in research, education and clinical practice
Others
Essential
- Knowledge of the Clinical Governance framework of the NHS (including Research Governance). Ability to act within these parameters
- GMC registration or eligibility for GMC registration
Person Specification
Royal Free World Class Values
Essential
- Demonstrable ability to meet the Trust Values
Education & professional Qualifications
Essential
- MBBS or equivalent
- Full GMC registration with license to practice
- Good Clinical Practice Training Certificate
Desirable
- Membership of relevant Royal College or oversees equivalent
Experience
Essential
- Work in a clinical trials or research environment
- Experience in data collection, management, analysis and presentation
Desirable
- Relevant experience in medical specialities
- Experience in transplant or immunology field
- Involvement in the clinical audit process and an understanding of the aims thereof
Skills and aptitudes
Essential
- Excellent communication skills/verbal and written
- Ability to take on tasks and responsibilities in a multi-professional team and to be able to work effectively and sensitively within it
Desirable
- Proven ability in relevant subject areas
Personal Qualities and atributes
Essential
- Ability to organise and prioritise workload
- High ethical and professional standards in research, education and clinical practice
Others
Essential
- Knowledge of the Clinical Governance framework of the NHS (including Research Governance). Ability to act within these parameters
- GMC registration or eligibility for GMC registration
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).
Employer details
Employer name
Royal Free London NHS Foundation Trust
Address
Royal Free Hospital
Pond Street
Hampstead
NW3 2QG
United Kingdom
Employer's website
Employer details
Employer name
Royal Free London NHS Foundation Trust
Address
Royal Free Hospital
Pond Street
Hampstead
NW3 2QG
United Kingdom